
Rare Disease Awareness Day - February 28
Professor Dr. Suresh K. Guptan, a rare disease specialist, neuroscientist, and director of India’s first and only Rare Disease Research Center, shares vital information with the global community. As of now, over 4,001 rare diseases have been officially identified in India, while globally, the number reaches around 7,000. Among them, some of the most severe and commonly found in India include Guillain-Barré Syndrome (GBS), Paralysis, Motor Neuron Disease (ALS), Autism, Cerebral Palsy, Down Syndrome, Mosaic Down Syndrome, Cretinism, Migraine, Alzheimer’s, and Parkinson’s.
Rare diseases are classified based on prevalence, and a condition is considered rare when it affects between 1 in 100,000 to 1 in 50 people. Some are even rarer, occurring in 1 in 10 million. These diseases are complex and often difficult to diagnose.
After 35 years of research, scientists have identified key factors behind these conditions. One of the major causes is hormonal imbalances and nutrient deficiencies. The human body has nine endocrine glands and 55 hormones, among which the adrenal gland produces Dehydroepiandrosterone (DHEA), a crucial hormone. Low levels of DHEA and magnesium deficiency, often called the "lamp of life," are major contributors to many rare diseases. Another major factor is vitamin and mineral deficiencies in children. Lack of B-complex vitamins, especially B3 (Niacin, Niacinamide), sulfur, Vitamin D2, D3, B12, folic acid, and iron, is linked to congenital disorders and chronic illnesses.
The best way to protect against these conditions is to return to nature. Consuming organic, seasonal fruits and vegetables, getting at least eight hours of sleep to maintain healthy DHA levels, and increasing magnesium intake through almonds, cashews, green leafy vegetables, and pulses are essential steps. Including sprouted legumes in the diet and drinking at least three to four liters of pure water daily helps maintain overall health. Exposure to sunlight for natural Vitamin D, ensuring mental well-being, and managing stress are equally important, as stress plays a crucial role in triggering diseases. Processed foods, artificial additives, bakery products, and junk food should be avoided as much as possible.
Kerala is turning into a "paradise of hospitals" with overcrowded medical facilities. The primary cause of this health crisis is the increasing use of artificial food additives to enhance taste, color, and aroma. Unfortunately, Malayalis prioritize taste over health, leading to a surge in diseases. Studies have shown that eliminating processed foods for six months can significantly improve overall health and prevent many illnesses.
By embracing a natural way of living, following simple diets, and ensuring mental and physical well-being, we can prevent many rare diseases. Wishing everyone a meaningful Rare Disease Awareness Day.
- Written by Jubaidath Beevi S.
(2024 Dr. B.R. Ambedkar Award Winner, Kollam)
"Lokah Samastah Sukhino Bhavantu" (May all beings be happy and healthy).

A valued motivation counseling Dr Suresh k guptan PhD DSC
medical research scientist palakkad

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